Are The Messenger RNA (mRNA) Vaccines Safe?

An infographic describing mRNA vaccine safety. The text below fully describes the graphic content.
Credit: Cody Shipman, CoVPN

YES! Long-term safety is still being studied. The Moderna vaccine trial included approximately 30,000 people 18 years and older in the USA. The Pfizer vaccine trial included approximately 43,000 people 16 years and older in the USA, Argentina, Brazil, and South Africa.

Most side effects happen within 7 days of vaccination and last 1-3 days. More people reported side effects following the second dose.

Mild to Moderate Symptoms Were Commonly Reported and Were Similar to Approved Vaccines for Other Viruses

Symptoms include:

  • Injection site soreness
  • Fatigue
  • Headaches
  • Body aches

Some participants had other health conditions during the studies that the FDA believes were unrelated to the vaccines.

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We need your help to keep learning and improving vaccines against COVID-19. We made history with safe and effective vaccines and we’ll keep working as long as there are people to protect, variants emerging, and research answers needed to end this pandemic. To participate:

  • Fill out the survey again so we have your most current information to match you with a study, even if you filled it out previously!
  • If you haven’t registered to volunteer before, sign up today. There’s still a lot we can do together for those we love.


Content last reviewed on May 19, 2021